B. Walsh

Brian Walsh

Scientific Advisor

Brian Walsh, Ph.D., joined Parker Highlander after managing the intellectual property for Rubicon Genomics and later Takara Bio USA in Ann Arbor, Michigan. Prior to that, Brian earned his Ph.D. in Molecular, Cellular, and Developmental Biology from the University of Michigan. Brian’s graduate work focused on DNA replication and repair, characterizing the replication and repair machinery of the bacterium Bacillus subtilis. Prior to his graduate work, Brian worked as a technician at Asterand Bioscience in Detroit and in bioprocess development at Pfizer, and earned his B.S. in Microbiology and Molecular Genetics from Michigan State University. Brian’s expertise includes drafting and prosecution of patents related to various areas of biotechnology including genomics and next generation sequencing technologies, stem cell biology, cancer therapeutics, and biologics.

Publications

  • Walsh BW, Bolz SA, Wessel SR, Schroeder JW, Keck JL, Simmons LA. (2014) RecD2 helicase limits replication fork stress in Bacillus subtilis. J. Bacteriol. PMID: 24443534
  • Marceau AH, Bernstein DA, Walsh BW, Shapiro W, Simmons LA, Keck JL. (2013) Protein interactions in genome maintenance as novel antibacterial targets. PLoS ONE. PMID: 23536821
  • Walsh BW, Lenhart JS, Schroeder JW, Simmons LA. (2012) Far Western blotting as a rapid and efficient method for detecting interactions between DNA replication and DNA repair proteins. Methods Mol Biol. PMID: 22976184
  • Lenhart JS, Schroeder JW, Walsh BW, Simmons LA. (2012) DNA repair and genome maintenance in Bacillus subtilis. Microbiol Mol Biol Rev. PMID: 22933559
  • Klocko AD, Schroeder JW, Walsh BW, Lenhart JS, Evans ML, Simmons LA. (2011) Mismatch repair causes the dynamic release of an essential DNA polymerase from the replication fork. Mol Microbiol. PMID: 21958350
  • Dupes NM, Walsh BW, Klocko AD, Lenhart JS, Peterson HL, Gessert DA, Pavlick CE, Simmons LA. (2010) Mutations in the Bacillus subtilis beta clamp that separate its roles in DNA replication from mismatch repair. J Bacteriol. PMID: 20453097
  • Klocko AD, Crafton KM, Walsh BW, Lenhart JS, Simmons LA. (2010) Imaging mismatch repair and cellular responses to DNA damage in Bacillus subtilis. J Vis Exp. PMID: 20142799

Educational Background

  • 2015 – Ph.D., Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI
  • 2006 – B.S., Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI

Contact Us

  • 1120 S. Capital of Texas Highway
  • Building One, Suite 200
  • Austin, TX 78746
  • Phone: 512-334-2900
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